Dr. Cameron Kyle-Sidell is an ED-ICU Doc at Maimonides in New York, currently under the COVID fire. He put up an inflammatory tweet yesterday which caused a lot of different reactions, because it clearly challenged the widespread even if only recent belief that one should intubate the COVID patients quite early, usually much earlier than one would in typical respiratory failure:
Very interesting. My experience is zero cases so far with COVID-19. Just some thoughts for what it’s worth from someone with no experience with COVID: Hypoxia is due to V/Q mismatch, diffusion, hypoventilation, low pO2 (altitude), shunt, low cardiac output (as more O2 is extracted off HgB and mixed venous O2 is low), and finally hemoglobin problems (whether by poisoning or defective HgB).